TOR — Arabidopsis thaliana

Summary

AT1G50030 (TOR) in Arabidopsis thaliana encodes a protein with protein serine/threonine kinase activity and phosphatidylinositol 3-kinase activity, containing FAT, FATC, FRB, and catalytic domains characteristic of the target of rapamycin family. TOR is associated with TORC1 signaling, positive regulation of rRNA processing, rRNA transcription, translation reinitiation, macroautophagy, mitophagy, ER-phagy, and negative regulation of autophagy. It is linked to stem cell proliferation, sister chromatid segregation, cytoplasmic streaming, and glutamine metabolism. The protein localizes to the cytoplasm, nucleus, plasmalemma, and ribosome. TOR is associated with seed size, biomass yield, photosynthetic rate, water use efficiency, root and leaf growth, cell proliferation and expansion, embryo and endosperm development, virus resistance, thermotolerance, circadian rhythm, and responses to abscisic acid, auxin, and jasmonic acid. Related genes in other species are linked to yield potential, water-use efficiency, fruit ripening, and pathogen resistance.