MYCGR3G90584 — Zymoseptoria tritici

Summary

MYCGR3G90584 (tsc2) on Zymoseptoria tritici chromosome 2 encodes a protein with GTPase-activating protein (GAP) activity and contains a Rap/Ran-GAP domain and a tuberin N-terminal domain. The gene is associated with the TSC1-TSC2 complex and localises to the cytoplasm, cytosol and nucleus. It is linked to the negative regulation of TOR and TORC1 signalling, positive regulation of autophagy, negative regulation of G1/S cell cycle transition, and regulation of small GTPase-mediated signal transduction. Associations also include amino acid import, leucine uptake, upregulation of L-leucine import, activation of L-arginine uptake, protein farnesylation, cAMP signalling, endocytosis, meiosis, and regulation of cell growth.