MYCGR3G85040 — Zymoseptoria tritici

Summary

YKU70 (KU70, MYCGR3G85040) on Zymoseptoria tritici chromosome 3 encodes the ATP-dependent DNA helicase II subunit 1, a protein with ATP hydrolase, 3'-5' DNA helicase, damaged DNA binding, telomere binding, and RNA binding activities. The product localises to the nucleus, Ku70:Ku80 complex, heterochromatin, subtelomeres, and sites of double-strand breaks. It is associated with non-homologous end joining, homologous recombination repair, base excision repair, interstrand crosslink repair, telomere capping, DNA integration, retrotransposition, replication fork processing, stalled replication fork localisation to the nuclear periphery, cell cycle phase, inositol phosphate metabolism, and nuclear movement. Related genes in other species are linked to oxidative stress tolerance.