MYCGR3G52873 — Zymoseptoria tritici

Summary

MYCGR3G52873, also known as CGA1 or GPA1, encodes a guanine nucleotide-binding protein alpha subunit in Zymoseptoria tritici on chromosome 1. The product possesses GTPase activity, binds GTP and metal ions, and is a component of the heterotrimeric G-protein complex localised to the cytoplasm. This gene is associated with GPCR signaling, cAMP metabolism, and the regulation of conidium formation, sexual sporocarp development, and secondary metabolite biosynthesis including sterigmatocystin, melanin, and penicillin anabolism. It has also been linked to seedling development, seed germination, maintenance of cell polarity, ruffle assembly, and response to iron. Studies of related genes in other species link the family to loss of pathogenicity and reduced virulence, as well as effects on germination rate.