RGA5 — Triticum turgidum subsp. durum

Summary

TRITD6AV1G225270, also known as RGA5 or Sr13, encodes a disease resistance N-terminal domain-containing protein with NB-ARC, LRR, and RX-like_CC domains, and is annotated for nucleotide, ADP, ATP, and metal binding. This durum wheat gene on chromosome 6A is associated with stem rust resistance, wheat leaf rust disease response, and defence responses to bacteria and other organisms. It is linked to innate immune response-activating signaling, regulation of pattern recognition receptor signaling, antiviral response, and hypersensitive response programmed cell death. The encoded protein localises to the cytosol, cytoplasm, and plasmalemma. Studies of related genes in other species connect the family to AAA+ ATPase and leucine-rich repeat domains.