GS2 — Triticum turgidum subsp. durum

Summary

TRITD6AV1G201020 (GS2, also known as TtGRF6, TtGRF5, TtGRF3, GRF2, GRF1, GS2, GRF3, GRF6, GRF5, TtGRF2, TtGRF1) on durum wheat chromosome 6A encodes a growth-regulating factor (GRF) protein with a WRC domain and QLQ motif, and exhibits APG8 ligase activity and transcription coactivator activity. The gene is associated with grain weight, grain filling period, seed weight, grain protein content, water use efficiency, anthocyanin content, and oxidative stress response. It is associated with seed development, root meristem growth, cell division, response to gibberellin, and regulation of gene expression. The encoded protein localizes to the nucleus, cytoplasm, and the Atg12-Atg5-Atg16 complex. Studies of related genes in other species connect the family to leaf development, cell proliferation, and chloroplast proliferation, as well as heading date and growth.