ADH — Triticum turgidum subsp. durum

Summary

TRITD6AV1G218720 (symbol TtADH) on durum wheat chromosome 6A encodes an alcohol dehydrogenase class-3 protein, specifically an S-(hydroxymethyl)glutathione dehydrogenase with NAD(P)+ activity (EC 1.1.1.284). The product contains ADH_3, zinc-binding, and NAD(P)-binding domains. In durum wheat, this gene is associated with methanal catabolism, nitric oxide storage, and is localized to the cytosol. It has also been linked to nitrogen content. Studies of related genes in other species, including ADH1, ADH2, and ADH3, connect the family to broader alcohol metabolism, but these associations are not yet established for TtADH itself.