GAD — Triticum turgidum subsp. durum

Summary

TRITD5BV1G235450 (TtGAD) on durum wheat chromosome 5B encodes a pyridoxal phosphate-dependent decarboxylase with sphinganine-1-phosphate aldolase activity, calmodulin and calcium ion binding, and is annotated as glutamate decarboxylase (EC 4.1.1.15). The gene is associated with the GABA shunt, glutamate breakdown, sphingolipid breakdown, mRNA transcription, and responses to water, calcium ion detection, mechanical stimulus, and homeostasis. It localises to the ER membrane, plastid, mitochondria, cytosol, nucleus, and plasmodesma. TtGAD is linked to traits including shoot growth angle, germination rate, root development, leaf senescence, seed growth, flowering time, jasmonic acid content, stomatal closure time, abscisic acid sensitivity, and salt tolerance. Phenotypic associations include drought tolerance, heat stress tolerance, water-use efficiency, bacterial pathogen resistance, and nitrogen metabolism. Studies of related genes in other species connect the family to hypoxia response, flooding tolerance, herbivory resistance, and cold stress tolerance.