GAD — Triticum turgidum subsp. durum

Summary

TRITD4BV1G016030 (TtGAD) on durum wheat chromosome 4B encodes a glutamate decarboxylase with pyridoxal phosphate-dependent decarboxylase and transferase domains, exhibiting glutamate decarboxylase, sphinganine-1-phosphate aldolase, and carboxy-lyase activities, along with calmodulin and calcium ion binding. The gene is associated with the GABA shunt, glutamate breakdown, sphingolipid breakdown, and mRNA transcription. It has been linked to seed germination, response to water, cellular response to nitrogen starvation, mechanical stimulus response, and homeostasis. Associations include shoot growth angle, jasmonic acid content, stomatal complex closure time, germination rate, root development trait, leaf senescence trait, seed growth and development trait, flowering time trait, abscisic acid sensitivity, and salt tolerance. Phenotypic connections involve drought tolerance, heat stress tolerance, water-use efficiency, bacterial pathogen resistance, and GABA content. The protein localizes to the ER membrane, plastid, mitochondria, cytosol, nucleus, and plasmodesma.