IRT1 — Triticum turgidum subsp. durum

Summary

TRITD4AV1G201040, designated TtIRT1 on durum wheat chromosome 4A, encodes a ZIP family metal transporter with transmembrane transporter activity for copper, zinc, manganese, iron, and cadmium ions. The gene is associated with zinc accumulation in this species and with numerous metal-related processes including nickel and cadmium transport, cellular and multicellular iron homeostasis, and stress responses to zinc and hypoxia. TtIRT1 is associated with grain filling period, biomass production, chlorophyll content, photosynthetic efficiency, root and leaf development, and disease resistance. It is also linked to iron deficiency tolerance, cadmium detoxification and accumulation, and metal homeostasis. Studies of related genes in other species link the family to iron acquisition, cadmium uptake, and nickel accumulation, as well as to iron uptake and cadmium transport.