ICDH — Triticum turgidum subsp. durum

Summary

TRITD3BV1G138070 (ICDH, TtICDH) on durum wheat chromosome 3B encodes an NADP(+)-dependent isocitrate dehydrogenase (EC 1.1.1.42), a member of the isocitrate/isopropylmalate dehydrogenase family. The enzyme possesses NADP isocitric dehydrogenase activity and is associated with NADPH regeneration, the TCA cycle, glyoxylate cycle, and NAD(P) metabolism. It has been linked to brassinosteroid-mediated signalling, defence response to bacteria, and response to zinc. The protein localises to chloroplast thylakoid and stroma, mitochondria, plastid, cytosol, plasmalemma, apoplast, and plasmodesmata. Associations with agronomic traits include proline content, salinity tolerance, photosynthetic rate, and root morphology. Studies of related genes in other species connect the family to drought tolerance, leaf relative water content, net photosynthetic rate, chlorophyll content, and disease tolerance.