GAD — Triticum turgidum subsp. durum

Summary

TRITD3AV1G001240 (symbol GAD, preferred name TtGAD1) on durum wheat chromosome 3A encodes a protein with pyridoxal phosphate-dependent decarboxylase and transferase domains, and is annotated with glutamate decarboxylase, sphinganine-1-phosphate aldolase, pyridoxal phosphate binding, and calmodulin binding activities. The gene is associated with the GABA shunt, glutamate and sphingolipid breakdown, mRNA transcription, carboxylic acid metabolism, response to water, seed germination, and homeostasis. Its product localises to the ER membrane, ER, and cytosol. TtGAD1 is associated with grain filling period, growth stage, germination rate, and photosynthetic rate. Related genes in other species link the family to grain length, grain yield, protein and sugar content, nitrate uptake, and tolerances to drought, cold, salinity, and submergence.