GAD — Triticum turgidum subsp. durum

Summary

TRITD2AV1G192960 (symbol GAD, preferred name TtGAD2) on durum wheat chromosome 2A encodes a protein with pyridoxal phosphate-dependent decarboxylase and transferase domains, and is annotated with glutamate decarboxylase activity (EC 4.1.1.15) and sphinganine-1-phosphate aldolase activity. The protein binds pyridoxal phosphate and calmodulin, and is associated with glutamate breakdown, the GABA shunt, sphingolipid breakdown, mRNA transcription, carboxylic acid metabolism, response to water, seed germination, and homeostasis. It localises to the ER membrane, ER, and cytosol. The gene is linked to growth stage and germination rate. Related genes in other species connect the family to grain, seed, root, and shoot phenotypes, as well as dwarfism and sterility, while sequence similarity links the family to grain yield, sugar content, drought tolerance, and salt tolerance.