TH7 — Triticum turgidum subsp. durum

Summary

TRITD1AV1G191890, also known as TtTH7, encodes a thioredoxin H-type protein with oxidoreductase activity acting on sulfur-group donors and protein-disulfide reductase activity. It is associated with diverse biological processes including defense responses to bacteria, insects, and microbial phytotoxins, regulation of salicylic acid and jasmonic acid signaling pathways, systemic acquired resistance, and response to hypoxia. The gene has been linked to numerous agronomic traits such as resistance to wheat powdery mildew, stripe rust, common root rot, and bacterial blight, as well as drought sensitivity, aluminum response, leaf senescence, and stomatal closure. It localizes to multiple cellular compartments including the nucleus, chloroplast stroma, endoplasmic reticulum, plasmodesmata, and stress granules. Studies of related genes in other species connect the family to oxidative stress tolerance, pathogen resistance, and salt stress responses.