MDH — Triticum turgidum subsp. durum

Summary

TRITD1AV1G200920 (TtMDH) on durum wheat chromosome 1A encodes a malate dehydrogenase with NAD-L-malate dehydrogenase activity (EC 1.1.1.37), belonging to the malate dehydrogenase type 1 and lactate/malate dehydrogenase domain families. The gene is associated with malate metabolism, the TCA cycle, glyoxylate cycle, and carboxylic acid metabolism, as well as chloroplast organization, stroma protein import, and responses to heat, cold, and light stimulus. It has been linked to photosynthetic rate, respiration rate, chloroplast development, and high temperature stress response. Associations also include salt and oxidative stress tolerance, thermomemory, and plastid genome stability. The product localizes to plastid stroma, chloroplast inner membrane and envelope, mitochondrial lumen, and the Ycf2/FtsHi complex. Studies of related genes in other species connect the family to salt tolerance, chloroplast development under heat stress, and stress tolerance.