IRT1 — Triticum turgidum subsp. durum

Summary

TRITD0UV1G113480, designated IRT1 in durum wheat, encodes a metal ion transmembrane transporter with activity for copper, zinc, manganese, iron, and cadmium, and also binds phosphoinositides, ubiquitin, mRNA, and proteins. It is associated with zinc accumulation, iron homeostasis, and responses to iron deficiency, cadmium, and chromium stress. The gene is linked to grain filling, chlorophyll content, photosynthetic efficiency, biomass production, root and leaf development, and disease resistance. It localizes to the plasma membrane, endosomes, and the ESCRT-I complex, and is associated with processes including cellular iron homeostasis, leaf senescence, and response to hypoxia. Related genes in other species link the IRT1 family to iron acquisition, cadmium uptake, and metal homeostasis.

Annotations

Chromosome
Un
Related genes
IRT1, IDF1, FREE1, IRT2, ZIP10, ZIP3, ZIP7, ZIP5
GO terms
GO:0005575, homeostasis, syngamy, Cadmium Ion Transmembrane Transporter Activity, multicellular organismal iron ion homeostasis, Endosome, Metal Ion Transmembrane Transporter Activity, Late Endosome Membrane
Publications
35077969, 26165498, 23794026, 29547723, 17404382, 16684236, 35755678, 31115467
Traits
iron uptake, iron deficiency response, iron acquisition, abscisic acid sensitivity, lipid droplet turnover, lipid droplet degradation, cadmium uptake, cadmium detoxification