IRT1 — Triticum turgidum subsp. durum

Summary

TRITD0UV1G131200, designated IRT1 in durum wheat, encodes a protein with copper ion transmembrane transporter activity, zinc ion transmembrane transporter activity, metal ion transmembrane transporter activity, manganese ion transmembrane transporter activity, iron channel activity, cadmium ion transmembrane transporter activity, phosphoinositide binding, ubiquitin binding, mRNA binding, and protein binding. The gene is associated with zinc accumulation, iron homeostasis, cadmium detoxification and tolerance, metal uptake and transport, iron deficiency tolerance, chlorophyll content, grain filling period, biomass production, and responses to hypoxia, bacteria, and chromium stress. The encoded protein localises to the plasmalemma, endosome, late endosome membrane, TGN, ESCRT I complex, nucleus, and extracellular space. Studies of related genes in other species link the family to iron acquisition, cadmium uptake, zinc homeostasis, and vacuolar biogenesis.