IRT1 — Triticum turgidum subsp. durum

Summary

TRITD0UV1G118690, designated IRT1 in durum wheat, encodes a metal ion transmembrane transporter with activity for copper, zinc, manganese, iron, and cadmium ions, and also exhibits phosphoinositide, ubiquitin, mRNA, and protein binding. The gene is associated with zinc accumulation, iron homeostasis, and responses to iron deficiency and cadmium stress. It is linked to leaf senescence, cellular response to hypoxia, and downregulation of abscisic acid signaling. Localization evidence connects the product to the plasma membrane, endosome, late endosome membrane, and ESCRT I complex. The gene has been associated with grain filling period, biomass production, chlorophyll content, photosynthetic efficiency, disease resistance, and root and leaf development. Studies of related genes in other species link the family to iron acquisition, cadmium uptake, and nickel accumulation.

Annotations

Chromosome
Un
Related genes
IRT1, IDF1, FREE1, IRT2, ZIP10, ZIP3, ZIP7, ZIP5
GO terms
GO:0005575, homeostasis, syngamy, Cadmium Ion Transmembrane Transporter Activity, multicellular organismal iron ion homeostasis, Endosome, Metal Ion Transmembrane Transporter Activity, Late Endosome Membrane
Publications
35077969, 26165498, 23794026, 29547723, 17404382, 16684236, 35755678, 31115467
Traits
iron uptake, iron deficiency response, iron acquisition, abscisic acid sensitivity, lipid droplet turnover, lipid droplet degradation, cadmium uptake, cadmium detoxification