CYP — Sorghum bicolor

Summary

SORBI_3010G085600, designated SbSQN (also known as CYP), encodes a protein with a cyclophilin-type PPIase domain and tetratricopeptide repeats. It is associated with cis-trans proline isomerase activity, cyclosporin A binding, histone binding, chromatin binding, calcium ion binding, U2 snRNA binding, U5 snRNA binding, and EC 5.2.1.8. In sorghum, SbSQN is associated with activation of secondary metabolite biosynthesis, regulation of ARF protein signal transduction, alternative mRNA splicing, chaperone-mediated protein complex assembly, basipetal auxin transport, and responses to chlorate, mannitol, and arsenic. The gene is linked to variegated leaf, bacterial disease response, temperature stress response, starch grain synthesis, sucrose content, phototropism response, root hair length, chloroplast development, jasmonic acid content, flowering time, and leaf senescence. It localizes to the mitochondrial ribosomal small subunit, Golgi stack, multivesicular body, secretory vesicle, and stress granule. Studies of related genes in other species connect the family to root development, auxin transport, abiotic stress tolerance, grain weight, and innate immunity.