G2 — Sorghum bicolor

Summary

SORBI_3010G107400 (SbG2) on sorghum chromosome 10 encodes a protein with domains including ACP_syn_III_C, 3-ktacl-CoA_syn, FAE1_typ3_polyketide_synth, and Thiolase-like, and is annotated with acridone synthase activity, naringenin-chalcone synthase activity, and multiple fatty acid elongation activities. The gene is associated with very-long-chain fatty acid and wax biosynthesis, cutin-based cuticle development, suberin biosynthesis, polyketide and sphingolipid metabolism, pigmentation, UV protection, trichome papilla formation and branching, pollen tube development, and cellular response to cold. It is linked to traits including drought and salt tolerance, high temperature and oxidative stress responses, abscisic acid sensitivity, flowering time, male sterility, leaf vein morphology, root mass density and thickness, chloroplast development, and disease tolerance. The encoded protein localises to the endoplasmic reticulum membrane, fatty acid elongase complex, cell wall, chloroplast, and mitochondria. Studies of related genes in other species connect the family to cuticular wax deposition, root suberin biosynthesis, chilling tolerance, and grain weight.