G2 — Sorghum bicolor

Summary

SORBI_3010G108200, also known as SbG2, encodes a 3-ketoacyl-CoA synthase, a member of the chalcone/stilbene synthase superfamily with domains including FAE1-type polyketide synthase and thiolase-like regions. The gene product exhibits trihydroxybenzophenone synthase, tetrahydroxybenzophenone synthase, naringenin-chalcone synthase, and acyltransferase activities, and is associated with protein homodimerization. SbG2 is linked to multiple biosynthetic processes, including wax, anthocyanin, flavonoid, fatty acid, and polyketide anabolism, as well as malonyl-CoA and benzoyl-CoA metabolism. It has also been connected to pigmentation, UV protection, nitrogen fixation, and nitric oxide storage. The protein localizes to membranes. Studies of related genes in other species further link this family to chalcone synthase and benzophenone synthase activities.