GCR1 — Sorghum bicolor

Summary

SORBI_3010G074900 (symbol GCR1, SbGCR1) on sorghum chromosome 10 encodes a protein with a GPCR_2-like_7TM domain and GCR1-cAMP receptor family signature. The product exhibits GTPase inhibitor, channel regulator, GPCR, GTPase binding, GTPase, GTP binding, and protein binding activities. SbGCR1 is associated with the heterotrimeric G-protein complex, plasmalemma, ER membrane, Golgi, and plasmodesmata. It is linked to adenylate cyclase-activating GPCR signaling, regulation of IP3 biosynthesis, membrane and thylakoid organization, maintenance of seed dormancy, stomatal closure regulation, blue light signaling, ROS metabolism, and responses to glucose and gibberellic/abscisic acid signaling. Associations include seed yield, germination rate, seedling growth, root length and thickness, cold and heat tolerance, disease tolerance, salt tolerance, nitrate sensitivity, anthocyanin content, stomatal resistance, and fruit growth. Studies of related genes in other species link the family to seed dormancy, flowering time, cytokinin and ABA sensitivity, sugar signaling, and blue light-induced phenylalanine production.