GAD — Sorghum bicolor

Summary

SORBI_3006G095700 (symbol GAD) on sorghum chromosome 6 encodes a glutamate decarboxylase, a pyridoxal phosphate-dependent enzyme with glutamate decarboxylase activity (EC 4.1.1.15) and sphinganine-1-phosphate aldolase activity. The product binds pyridoxal phosphate and calmodulin, and is localized to the ER membrane, ER, and cytosol. This gene is associated with glutamate breakdown, sphingolipid breakdown, glutamate metabolism, and carboxylic acid metabolism. It is associated with grain yield and drought tolerance. Studies of related genes in other species link the family to sugar content, growth stage, germination rate, seed germination, and salt tolerance.