HSP70 — Sorghum bicolor

Summary

SORBI_3006G055600, designated HSP70 on sorghum chromosome 6, encodes an ATP-dependent protein folding chaperone belonging to the Hsp70 family, with ATP hydrolase activity, ATP binding, and heat shock protein binding functions. This gene is associated with protein folding in the endoplasmic reticulum, protein refolding, the ERAD pathway, and the ER unfolded protein response. It is associated with response to heat, response to stress, response to virus, detoxification, protein breakdown, programmed cell death, and cell death. The encoded product localizes to the ER chaperone complex, ER lumen, chloroplast membrane, tonoplast, membrane, cytoplasm, and nucleus, with additional association to the axonemal central pair projection. HSP70 is associated with heat tolerance. Studies of related genes in other species associate the family with spikelet number and cold tolerance.