HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400035185, designated HMG1 on potato chromosome 9, encodes a 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, a member of the HMG_CoA_Rdtase family with hydroxymethylglutaryl-CoA reductase (NADPH) activity and protein binding capability. The gene is associated with the mevalonate pathway, isoprenoid metabolism, sterol and triterpenoid anabolism, phytoalexin biosynthesis, and saponin production. It has been linked to steroidal glycoalkaloid content in potato, as well as plant height, flowering time, flower morphology and color, male fertility, senescence, and defense and wound responses. Associations extend to photosynthetic rate, protein content, seed phytosterol content, and cardenolide production. The product localizes to the endoplasmic reticulum, peroxisome membrane, chloroplast membrane, and nucleus. Studies of related genes in other species link the family to isoprenoid biosynthesis, phytosterol content, and mevalonate pathway regulation.
Annotations
- Chromosome
- 9
- Related genes
- HMG1, HMG2
- GO terms
- protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, Chloroplast Membrane, Systemic Acquired Resistance, Flower Development, Response To Wounding, Response To Jasmonic Acid
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development