M2 — Solanum tuberosum

Summary

StM2 (PGSC0003DMG400006623) on potato chromosome 6 encodes a protein with a cyclophilin-type PPIase domain and a cyclophilin-like domain superfamily fold. The protein is annotated with cis-trans proline isomerase activity, cyclosporin A binding, salicylic acid binding, peroxidase activity, U2 and U5 snRNA binding, GTP:GDP antiporter activity, L-serine O-acetyltransferase activity, and histone and chromatin binding. It localizes to the Golgi stack, thylakoid lumen, proteasome, and secretory vesicles. StM2 is associated with protein proline isomerization, chaperone-mediated protein complex assembly, alternative mRNA splicing, response to light intensity, wound healing, and regulation of ARF protein signal transduction. The gene is linked to traits including variegated leaf, starch grain synthesis, respiration rate, photosynthetic rate, sucrose content, root hair length, meristem identity, chloroplast development, jasmonic acid content, and heat stress tolerance. Related genes in other species connect the family to pre-mRNA splicing and heat stress tolerance, as well as water stress tolerance and hydrotropism.