M2 — Solanum tuberosum

Summary

StM2 (PGSC0003DMG400006624) on potato chromosome 6 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase, a protein with cyclophilin-like domains that also exhibits annotated activities including GTP:GDP antiporter, U5 and U2 snRNA binding, L-serine O-acetyltransferase, cyclosporin A binding, peroxidase, salicylic acid binding, histone and chromatin binding, and protein tag functions. The gene is associated with diverse biological processes such as protein proline isomerization, regulation of ARF protein signal transduction, alternative mRNA splicing, response to light intensity, wound healing, cell adhesion, and cysteine anabolism. It is linked to numerous traits including variegated leaf, starch grain synthesis, respiration rate, temperature stress response, zinc sensitivity, phototropism, sucrose content, herbicide sensitivity, jasmonic acid content, photosynthetic rate, and chloroplast development. Localization evidence connects the product to the Golgi stack, thylakoid lumen, stromule, secretory vesicle, and proteasome. Studies of related genes in other species link the family to hydrotropism, phototropism, cold and drought stress tolerance, embryo patterning, and resistance to Botrytis cinerea.