SEN1 — Solanum tuberosum

Summary

PGSC0003DMG400007497, designated StSEN1 on potato chromosome 6, encodes a tRNA-intron lyase (EC 4.6.1.16) with nuclease activity and nucleic acid binding, belonging to the tRNA_intron_Endonuc_N domain family. The gene is associated with tRNA processing, including intron splice site recognition and cleavage, as well as mRNA processing and defense response. StSEN1 has been directly linked to resistance against Synchytrium endobioticum and potato wart disease. Additional associations include phosphate starvation response, hypocotyl elongation, zygote division, leaf senescence, and plant defense response. The encoded protein localizes to the SEN complex, membrane, mitochondria, cytoplasm, and nucleus. Studies of the Arabidopsis relative SEN2 connect the family to tRNA splicing, while sequence similarity links related genes in other species to leaf and stem senescence traits, chlorophyll content, and root morphology.