F3H — Solanum tuberosum

Summary

PGSC0003DMG400003563, the potato F3H gene on chromosome 2, encodes a 2-oxoglutarate-dependent dioxygenase with flavanone 3-dioxygenase, flavonol synthase and flavone synthase activities. It is associated with flavonoid, anthocyanin, coumarin, lignin and phenylpropanoid metabolism, pigmentation, and responses to UV-B, auxin and fungal molecules. The gene is linked to anthocyanin content, flower and leaf color, flavonoid content, UV-B light sensitivity, oxidative stress response, and salt tolerance. It has been connected to powdery mildew resistance, pollen thermotolerance, cold acclimation, root hair and lateral root formation, and circadian clock regulation. The protein localises to the cytosol, nucleus, endoplasmic reticulum and tonoplast. Studies of related genes in other species link the family to proanthocyanidin accumulation and seed coat pigmentation, and to stress tolerance.