AS1 — Solanum tuberosum

Summary

PGSC0003DMG400004170, designated AS1 or ASN1 on potato chromosome 6, encodes an asparagine synthase (glutamine-hydrolyzing) (EC 6.3.5.4) with ATP-binding activity, placing it in the AsnB_N and Asn_synthase domain families. The gene is associated with L-asparagine anabolism, amino acid breakdown, and cellular responses to sucrose, glucose, fructose, and sucrose starvation, as well as response to absence of light and stress. It has been linked to acrylamide formation, nitrogen metabolism, nitrogen reutilization, leaf senescence, and salt stress response. Associations with reducing sugar content, amylose content, starch content and mobilization, seed protein content, stomatal resistance and opening, and phosphate starvation tolerance have also been noted. The protein localizes to the cytosol and cytoplasm. Related genes in other species link the family to seed nitrogen content and leaf senescence traits.