DFR — Solanum tuberosum

Summary

PGSC0003DMG400003605, designated DFR on potato chromosome 2, encodes a protein with flavanone 4-reductase and dihydroflavanol 4-reductase activities (EC 1.1.1.234, EC 1.1.1.219), placing it in the NAD(P)-binding domain superfamily. The gene is associated with the regulation of anthocyanin, flavonoid, and phenylpropanoid biosynthesis, as well as pigmentation of flowers, tubers, and seeds. It has been linked to agronomically important traits including tuber and flower color, anthocyanin content, starch content, photosynthetic ability, canopy temperature, and responses to UV-B light, low temperature, oxidative stress, and nitrogen stress. Additional associations include root gravitropic response, pollen fertility, pathogen and nematode resistance, and antioxidant capacity. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast.