M2 — Solanum lycopersicum

Summary

SlM2 (SOLYC08G006090.3) encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) on tomato chromosome 8, a member of the cyclophilin A-like family that also exhibits annotated molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, L-serine O-acetyltransferase activity, cyclosporin A binding, salicylic acid binding, peroxidase activity, histone and chromatin binding, and protein dimerization activity. The gene is associated with diverse biological processes such as protein proline isomerization, androgen anabolism, RNA positioning, regulation of ARF protein signal transduction, actin depolymerization, and endosome transport via the MVB sorting pathway. It is linked to traits including fruit dry weight and size, sucrose content, photosynthetic rate, respiration rate, leaf necrosis, variegated leaf, root branching and hair length, meristem development, auxin and jasmonic acid sensitivity, temperature stress response, herbicide sensitivity, and zinc sensitivity. Related genes in other species are associated with heat stress tolerance, pre-mRNA splicing, pathogen defense, root hydrotropism, gravitropism, auxin transport, embryo patterning, and membrane trafficking.