FLS2 — Solanum lycopersicum

Summary

SOLYC08G044305.1, the tomato FLS2 gene on chromosome 8, encodes a transmembrane receptor protein serine/threonine kinase with leucine-rich repeat domains. The product exhibits signaling receptor activity, protein kinase activity, and binds ATP, steroids, and SNARE proteins. FLS2 is associated with PTI signalling, the MAPK cascade, endocytosis, membrane fission, cytokinesis, and immune evasion. It has been linked to bacterial disease response, self-incompatibility, and stomatal resistance. The protein localizes to the plasma membrane, ER membrane, endosome, and nucleus. Studies of related genes in other species connect the family to disease resistance and stomatal development regulation.