co-2 — Solanum lycopersicum

Summary

SOLYC08G074683.1, the co-2 gene on tomato chromosome 8, encodes a polyphenol oxidase (PPO) containing a tyrosinase copper-binding domain and a di-copper centre, with annotated catecholase activity and copper binding. This gene is associated with lycopene breakdown, melanin anabolism, and response to phenylpropanoids, and its product localises to the chloroplast thylakoid lumen. It has been linked to numerous agronomic traits, including lycopene content, fruit firmness, seed coat and stigma color, percent germination, seedling height and vigor, stem thickness, root volume, harvest index, leaf trichome density, relative chlorophyll content, and responses to fungal and bacterial diseases, as well as parasitic weed. Additional associations include copper and phosphorus concentration, growth hormone content, carbohydrate and soluble protein content, and cytoplasmic male sterility. Studies of related genes in other species support the enzyme classification 1.10.3.1.