HSP90 — Solanum lycopersicum

Summary

SOLYC04G081630.2, the tomato HSP90 gene on chromosome 4, encodes an ATP-dependent protein folding chaperone with ATP hydrolase activity, belonging to the Hsp90 family and containing an HSP90_C domain. The encoded protein is localised to the cytosol, cytoplasm, ER lumen, plasmalemma, and perinuclear region. This gene is associated with diverse biological processes including cellular response to heat, autophagy, induced systemic resistance, calcium and H2O2-mediated signaling, metabolic burst, and the ascorbate-glutathione cycle, as well as chlorophyll metabolism, steroidogenesis, and auxin, ethylene, and nitric oxide anabolism. It is also linked to proteasome degradation, nuclear export, RNA anabolism, oviposition, and protein stabilization. Associations with agronomically relevant traits include drought tolerance, leaf temperature, chlorophyll content, quantum yield, photochemical quenching, and root system architecture traits such as root length, lateral root number, and root number, as well as amino acid content. Studies of related genes in other species identify the family as including endoplasmin and GRP-94 homologs.