ADH1 — Solanum lycopersicum

Summary

SOLYC04G082180.4 (ADH1) on tomato chromosome 4 encodes a protein with ADH_Zn_CS, ADH-like_N, and ADH-like_C domains, and exhibits S-(hydroxymethyl)glutathione dehydrogenase activity (NAD(P)+-dependent) as well as aldo-keto reductase (NAD) activity and zinc binding. The gene is associated with ethanol, fumonisin, melanin, glucan, and polyketide anabolism, methanal catabolism, oxygen transport, energy homeostasis, and response to stimulus. It is linked to fructose, glucose, and sugar content, fruit firmness and color, and carotenoid, carotene, and flavonoid content. Associations also include drought tolerance, oxidative stress response, and salt tolerance. The encoded protein localises to the cytosol. Studies of related genes in other species connect the family to EC 1.1.1.1 and EC 1.1.1.284 activities.