N — Solanum lycopersicum

Summary

SOLYC05G007850.2 (symbol Bs4, also known as N) on tomato chromosome 5 encodes a protein with NADP nucleosidase and DPNase activities, containing NB-ARC, TIR, LRR, and other domains characteristic of plant disease resistance proteins. The gene is directly associated with disease resistance and bacterial spot resistance in tomato. It has been linked to numerous biological processes including innate immune response signaling, programmed cell death, apoptotic process, thylakoid membrane disassembly, leaf abscission, NAD breakdown, and the mevalonate pathway. The encoded protein localizes to both the cytoplasm and nucleus. Additional associations include bacterial blight disease resistance, sugar content, and seed growth and development traits. Studies of related genes in other species connect the family to virus resistance and plant growth.