R1B-12 — Solanum lycopersicum

Summary

SlR1B-17 (SOLYC05G013280.4) on tomato chromosome 5 encodes a protein containing NB-ARC, Rx_N, and RX-like_CC domains characteristic of plant disease resistance proteins, with annotated ATP and ADP binding and metal binding molecular functions. The gene is associated with membrane and cytoplasmic localization. It has been linked to bacterial disease response and sugar content, as well as a wide range of biological processes including antigen processing, immune evasion, membrane depolarization, MAPK cascade, cell wall biogenesis, starch anabolism, cuticle anabolism, hormone anabolism, and metabolic burst. Additional associations include mitosis, nuclear import, vacuolar protein sorting, mRNA breakdown, TCA cycle, and protein targeting. Related genes in other species connect this gene family to disease resistance functions.