FLS2 — Solanum lycopersicum

Summary

SlFLS2 (SOLYC02G150128.1) on tomato chromosome 2 encodes a transmembrane receptor serine/threonine kinase with leucine-rich repeat domains, ATP binding, and protein kinase activity. The gene is associated with activation of immune response, PTI signalling, the MAPK cascade, and metabolic burst. It has been linked to bacterial disease response, stomatal resistance, and self-incompatibility. Localisation evidence connects the product to the plasma membrane, endosome, ER membrane, and nucleus. The gene is also associated with protein secretion, membrane fission, cytokinesis, and chemotaxis. Studies of related genes in other species link the family to non-specific serine/threonine protein kinase activity (EC 2.7.11.1) and plant LRR-RLK domains.