I-2 — Solanum lycopersicum

Summary

SlI-2 (SOLYC03G025980.3) on tomato chromosome 3 encodes a protein with protein phosphatase inhibitor activity, belonging to the PPI-2 family. In tomato, this gene is associated with resistance to Fusarium and other pathogens, as well as with programmed cell death, immune response, and regulation of signal transduction. It is also linked to protein secretion, digestion, and virus-induced PTGS. The encoded product localizes to the plastid and nucleus. Additionally, SlI-2 has been connected to fruit weight. Studies of related genes in other species link the family to Fusarium head blight response, abscisic acid sensitivity, salt tolerance, and disease tolerance, though these associations are not yet established in tomato.