CUM1 — Solanum lycopersicum

Summary

SlCUM1 (SOLYC03G005870.4) encodes a protein with translation initiation factor activity and RNA m7G cap binding, belonging to the TIF_eIF_4E family. In tomato, this gene is associated with virus resistance, particularly against cucumber mosaic virus, and has been linked to genetic variation. The encoded product is also annotated with linoleate 13S-lipoxygenase activity and salicylic acid binding, and is associated with lipid oxidation, jasmonic acid anabolism, green leaf volatile biosynthesis, and regulation of defense response. Associations extend to traits including leaf color, fruit shape, sugar content, drought tolerance, and responses to aphids, insects, and UV-B light. The protein localizes to the cytosol, plastid, stress granules, and P bodies. Studies of related genes in other species link the eIF4E family to viral resistance, salt tolerance, and abiotic stress tolerance.