M2 — Solanum lycopersicum

Summary

SlM2 (SOLYC01G108340.3) on tomato chromosome 1 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with a tetratricopeptide repeat (TPR) domain, and is annotated with activities including cyclosporin A binding, salicylic acid binding, histone binding, and peroxidase activity. The gene is associated with numerous traits such as fruit dry weight and size, sucrose content, photosynthetic rate, respiration rate, leaf necrosis, variegated leaf, root branching and hair length, auxin and jasmonic acid content, and responses to temperature stress, light intensity, and zinc. It is linked to processes including protein proline isomerization, androgen anabolism, RNA positioning, actin depolymerization, and endosome transport via the MVB sorting pathway, and localizes to the Golgi stack, thylakoid, and secretory vesicle. Studies of related genes in other species connect the family to heat stress tolerance, pre-mRNA splicing, root hydrotropism, auxin transport, and embryo patterning.