DDB1 — Solanum lycopersicum

Summary

SOLYC02G021650.3 (DDB1) on tomato chromosome 2 encodes a protein with domains characteristic of the RSE1/DDB1/CPSF1 family and possesses multiple annotated molecular functions including damaged DNA binding, ubiquitin ligase activity, and protein kinase inhibitor activity. In tomato, DDB1 is associated with carotenoid content and fruit pigmentation. The gene is linked to a wide range of biological processes including pigment accumulation, ethene metabolism, proteasome degradation, and response to UV-A. It is associated with traits such as fruit color, lycopene content, flavonoid content, leaf thickness, photoperiod sensitivity, and viral disease response. Localisation evidence places the product in the nucleotide-excision repair complex, PRC2 complex, and DCX complex. Studies of related genes in other species link the DDB1 family to floral transition, light signaling, disease resistance, and root architecture.