IRT1 — Solanum lycopersicum

Summary

SlIRT1 (SOLYC02G069200.3) encodes a member of the ZIP family of metal transporters, possessing metal ion transmembrane transporter activity for copper, manganese, zinc, iron, and cadmium, along with phosphoinositide and ubiquitin binding. In tomato, SlIRT1 is associated with cellular and multicellular iron homeostasis, zinc import and transport, manganese and nickel cation transport, cadmium transport, response to iron and nitrate, chlorophyll metabolism, pH reduction, tropism, and endosome membrane budding. The protein localises to the late endosome membrane, plasmalemma, trans-Golgi network, and nucleus. SlIRT1 is associated with iron deficiency tolerance and response, metal homeostasis, photosynthetic efficiency, chlorophyll content, chloroplast development, leaf development, lateral root development, plant growth promotion, disease resistance, cadmium detoxification and tolerance, leaf chlorosis, leaf curling, and protein content. Related genes in other species link the family to iron acquisition and translocation, cadmium sensitivity, and zinc tolerance.