I-2 — Solanum lycopersicum

Summary

SOLYC01G009610.3, the tomato I-2 gene on chromosome 1, encodes a protein with protein phosphatase inhibitor activity and belongs to the PPI-2 family. In tomato, I-2 is associated with Fusarium resistance, disease resistance, and pathogen resistance. The gene is linked to regulation of signal transduction, protein secretion, digestion, secretion, virus-induced PTGS, immune response, cell death, and programmed cell death, and its product localizes to the plastid and nucleus. Associations with fruit weight and disease tolerance have also been noted. Studies of related genes in other species connect the I-2 family to Fusarium head blight response, abscisic acid sensitivity, and salt tolerance, with related genes in other species linked to ABA signaling and salt tolerance.