DET1 — Solanum lycopersicum

Summary

SOLYC01G056340.4 (DET1) on tomato chromosome 1 encodes a de-etiolated protein 1 (Det1) family member with multiple molecular functions including phosphatidylethanolamine binding, phytochrome binding, damaged DNA binding, ubiquitin ligase substrate adaptor activity, blue light photoreceptor activity, FAD binding, and DNA-binding transcription factor activity. DET1 is associated with zeaxanthin, beta-carotene, carotene, and lycopene anabolism, pigment metabolism, regulation of tetrapyrrole anabolism, proteasome degradation, protein monoubiquitination, and responses to UV-A and water-immersion restraint stress. It localizes to several nuclear complexes including the CRL, SCF, and Cul4-RING E3 ubiquitin ligase complexes. In tomato, DET1 has been linked to antioxidant content and chlorophyll production. The gene is also associated with numerous traits including fruit morphology and number, flower number, leaf area and thickness, carotene content, blue light sensitivity, photoperiod sensitivity, and viral disease response. Studies of related genes in other species link the DET1 family to seed yield, inflorescence architecture, shade avoidance, and freezing tolerance.