HSP70 — Pisum sativum

Summary

PSAT3G178160 (HSP70) in garden pea (Pisum sativum, chromosome 3LG5) encodes a member of the heat shock protein 70 family, characterized by an ATPase nucleotide-binding domain and a peptide-binding domain. The product has ATP hydrolase activity, protein-folding chaperone activity, and heat shock protein binding activity. This gene is associated with a wide range of biological processes including protein folding and refolding, mitochondrial protein import and biogenesis, seed maturation, embryogenesis, cell development, DNA replication, the ERAD pathway, ER unfolded protein response, S-nitrosylation and S-transnitrosylation, and response to stress and virus. It localizes to the cytoplasm, nucleus, membrane, chloroplast membrane, ER lumen and chaperone complex, and axonemal central pair projection. Studies of related genes in other species link the HSP70 family to general stress responses and protein homeostasis.