HSP70 — Pisum sativum

Summary

PSAT3G178760 (HSP70) in garden pea (Pisum sativum) on chromosome 3LG5 encodes a member of the heat shock protein 70 family, characterized by an ATPase nucleotide-binding domain and a peptide-binding domain. The product has ATP hydrolase activity, protein folding chaperone activity, and heat shock protein binding activity. This gene is associated with a wide range of biological processes including protein folding and refolding, mitochondrial protein import and biogenesis, seed maturation, embryogenesis, response to stress and virus, S-nitrosylation, the ERAD pathway, and DNA replication. It is also linked to cell development, protein targeting, and the unfolded protein response in the endoplasmic reticulum. The protein localizes to the cytoplasm, nucleus, membrane, chloroplast membrane, ER lumen, and axonemal central pair projection. Related genes in other species confirm the family's role as a 70-kilodalton heat shock protein.