HSP70 — Pisum sativum

Summary

PSAT3G178200 (HSP70) in garden pea (Pisum sativum) on chromosome 3LG5 encodes a member of the heat shock protein 70 family, characterized by an ATPase nucleotide-binding domain and a peptide-binding domain, and is annotated with ATP hydrolase activity, ATP binding, protein folding chaperone activity, and heat shock protein binding. This gene is associated with mitochondrial protein import and biogenesis, protein targeting, the ERAD pathway, ER unfolded protein response, S-nitrosylation and S-transnitrosylation, cell development, embryogenesis, seed maturation, DNA replication, response to virus and stress, and protein refolding and folding. Its product localizes to the ER chaperone complex and lumen, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the HSP70 family to similar chaperone functions and stress responses.