GSH2 — Phaseolus vulgaris

Summary

PHAVU_006G094700, designated PvGSH2 or PvGSHB, encodes a glutathione synthase on French bean chromosome 6. The product possesses glutathione synthase activity, binds glutathione, ATP and magnesium, and forms homodimers. It is associated with glutathione anabolism, nitrogen fixation, nodulation, stress and jasmonic acid responses, and localises to plastids and cytosol. The gene is linked to cadmium and ozone tolerance, endoplasmic reticulum stress response and morphology, seedling and plant development, root growth, jasmonate hypersensitivity, and 2,4-dinitrotoluene response. Related genes in other species connect the family to glutathione and phytochelatin synthesis, cadmium and cesium resistance, stress tolerance, and seedling lethal phenotypes with glutathione deficiency.

Annotations

Chromosome
6
Related genes
GSH2
GO terms
Nitrogen Fixation, Plastid, Response To Jasmonic Acid, glutathione anabolism, Glutathione Synthase Activity, Cytosol, Glutathione Binding, GO:0009507
Publications
23496095, 21105929, 17137297, 28627464, PMID:25293756, PMID:15302873, 23691990, 33661984
Traits
glutathione biosynthesis, stress tolerance, cadmium resistance, other miscellaneous trait, Yellow Leaves, Reduced Size, Altered Glutathione Metabolism, Cadmium Sensitivity, Seedling Lethal, White Seedlings, Glutathione Deficiency, Bleached Embryo, Seedling Lethal, Partial Rescue with GSH, clim-tmin11